Hailed in the press as "One of the most versatile and musical drummers in music today", Paul Wertico was born January 5, 1953 in Chicago. He gained worldwide recognition as a member of the Pat Metheny Group from 1983 to 2001. During his tenure with Metheny, Wertico played on ten recordings and four videos, appeared on numerous television shows, and frequently toured around the world. He also won seven Grammy Awards (for "Best Jazz Fusion Performance," "Best Contemporary Jazz Performance," and "Best Rock Instrumental Performance"), magazine polls, and received several gold records.

In recent years, Wertico has continued to tour and perform around the world, as well as around the Chicago metropolitan area, where he is based. This led to the creation of his own band (the Paul Wertico Trio) and collaborations with jazz notables such as Larry Coryell, Kurt Elling, and Jeff Berlin. These collaborations enabled Wertico to be featured on group recordings in a variety of musical genres, and also gave him an opportunity to produce records. In 2009, Wertico's trio joined forces with Marbin, which consisted of Israeli musicians Danny Markovitch (saxophone) and Dani Rabin (guitar). The group performed as Paul Wertico's Mid-East/Mid-West Alliance, and recorded an album for the Chicago Sessions label that received accolades from publications such as the Chicago Tribune, DRUM!, and Modern Drummer. Wertico's current group is Wertico Cain & Gray, featuring multi-instrumentalists David Cain and Larry Gray. A 2013 recording by Wertico Cain & Gray, entitled Sound Portraits, won "Best Live Performance Album" in the 13th Annual Independent Music Awards (2014).

When not touring, Wertico divides his career doing session work, producing, composing, and leading his own groups, as well as teaching. Among the musicians with whom he has played are Eddie Harris, Lee Konitz, Dave Liebman, Sam Rivers, Bob Mintzer, Terry Gibbs, Buddy DeFranco, Roscoe Mitchell, Evan Parker, Jay McShann, Herbie Mann, Randy Brecker, Jerry Goodman, Ramsey Lewis, David Bowie, Charlie Haden, George Coleman, Diane Schuur, Nelson Riddle, Sonny Fortune, Ken Nordine, Tierney Sutton, and many others. Wertico is a member of the Larry Coryell Power Trio. From 2000 to 2007, he was a member of the platinum-record-winning Polish progressive rock band, SBB. He is also the inventor of TUBZ, made by Pro-Mark (who also makes the “Paul Wertico Signature Drum Stick”), as well as a new independently manufactured signature product called “Paul Wertico’s Acousticx”.